The Single-Leg-Stance Test in Parkinson’s Disease
Identifieur interne : 000908 ( Main/Exploration ); précédent : 000907; suivant : 000909The Single-Leg-Stance Test in Parkinson’s Disease
Auteurs : Taylor Chomiak [Canada] ; Fernando Vieira Pereira [Canada] ; Bin Hu [Canada]Source :
- Journal of Clinical Medicine Research [ 1918-3003 ] ; 2014.
Abstract
Timed single-leg-stance test (SLST) is widely used to assess postural control in the elderly. In Parkinson’s disease (PD), it has been shown that an SLST around 10 seconds or below may be a sensitive indicator of future falls. However, despite its role in fall risk, whether SLST times around 10 seconds marks a clinically important stage of disease progression has largely remained unexplored.
A cross-sectional study where 27 people with PD were recruited and instructed to undertake timed SLST for both legs was conducted. Disease motor impairment was assessed with the Unified Parkinson’s Disease Rating Scale Part 3 (UPDRS-III).
This study found that: 1) the SLST in people with PD shows good test-retest reliability; 2) SLST values can be attributed to two non-overlapping clusters: a low (10.4 ± 6.3 seconds) and a high (47.6 ± 11.7 seconds) value SLST group; 3) only the low value SLST group can be considered abnormal when age-matched normative SLST data are taken into account for comparison; and 4) lower UPDRS-III motor performance, and the bradykinesia sub-score in particular, are only associated with the low SLST group.
These results lend further support that a low SLST time around 10 seconds marks a clinically important stage of disease progression with significant worsening of postural stability in PD.
Url:
DOI: 10.14740/jocmr1878w
PubMed: 25584104
PubMed Central: 4285065
Affiliations:
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Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Pereira, Fernando Vieira" sort="Pereira, Fernando Vieira" uniqKey="Pereira F" first="Fernando Vieira" last="Pereira">Fernando Vieira Pereira</name><affiliation wicri:level="4"><nlm:aff id="Aa">Department of Clinical Neurosciences, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, AB, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Neurosciences, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Hu, Bin" sort="Hu, Bin" uniqKey="Hu B" first="Bin" last="Hu">Bin Hu</name><affiliation wicri:level="4"><nlm:aff id="Aa">Department of Clinical Neurosciences, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, AB, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Neurosciences, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, AB</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author></analytic><series><title level="j">Journal of Clinical Medicine Research</title><idno type="ISSN">1918-3003</idno><idno type="eISSN">1918-3011</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="a1"><title>Background</title><p>Timed single-leg-stance test (SLST) is widely used to assess postural control in the elderly. In Parkinson’s disease (PD), it has been shown that an SLST around 10 seconds or below may be a sensitive indicator of future falls. However, despite its role in fall risk, whether SLST times around 10 seconds marks a clinically important stage of disease progression has largely remained unexplored.</p></sec><sec id="a2"><title>Methods</title><p>A cross-sectional study where 27 people with PD were recruited and instructed to undertake timed SLST for both legs was conducted. Disease motor impairment was assessed with the Unified Parkinson’s Disease Rating Scale Part 3 (UPDRS-III).</p></sec><sec id="a3"><title>Results</title><p>This study found that: 1) the SLST in people with PD shows good test-retest reliability; 2) SLST values can be attributed to two non-overlapping clusters: a low (10.4 ± 6.3 seconds) and a high (47.6 ± 11.7 seconds) value SLST group; 3) only the low value SLST group can be considered abnormal when age-matched normative SLST data are taken into account for comparison; and 4) lower UPDRS-III motor performance, and the bradykinesia sub-score in particular, are only associated with the low SLST group.</p></sec><sec id="a4"><title>Conclusion</title><p>These results lend further support that a low SLST time around 10 seconds marks a clinically important stage of disease progression with significant worsening of postural stability in PD.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name 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McNamee</name></author><author><name sortKey="Carne, W" uniqKey="Carne W">W Carne</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li></country><region><li>Alberta</li></region><settlement><li>Calgary</li></settlement><orgName><li>Université de Calgary</li></orgName></list><tree><country name="Canada"><region name="Alberta"><name sortKey="Chomiak, Taylor" sort="Chomiak, Taylor" uniqKey="Chomiak T" first="Taylor" last="Chomiak">Taylor Chomiak</name></region><name sortKey="Hu, Bin" sort="Hu, Bin" uniqKey="Hu B" first="Bin" last="Hu">Bin Hu</name><name sortKey="Pereira, Fernando Vieira" sort="Pereira, Fernando Vieira" uniqKey="Pereira F" first="Fernando Vieira" last="Pereira">Fernando Vieira Pereira</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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